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Mukesh averages 7.03 across 34 rated films as an actor, ahead of Mohanlal at 6.94.
Dot size shows IMDb votes. Films with fewer than 1,000 votes sit on the baseline.
| Boeing Boeing | 1985 | 7.3 | as Shyam | as Anilkumar |
| Hello My Dear: Wrong Number | 1986 | · | as Venugopal | as Jacob |
| Mazha Peyyunnu Maddalam Kottunnu | 1986 | · | as Shambhu | as Shivan |
| Thalavattam | 1986 | 7.9 | as Vinod | as Hari |
| Moonnam Mura | 1988 | · | as Ali Imran | as Vinod |
| Vandanam | 1989 | 7.9 | as Unnikrishnan | as Peter Kallikal |
| Akkare Akkare Akkare | 1990 | 7.7 | as Ramdas (aka Dasan) | as Surendran |
| Kakkakuyil | 2001 | · | as Sivaraman | as Govindan Kutty |
| Vismayathumbathu | 2004 | · | as Sreekumar | as Govindan Kutty |
| Udayananu Tharam | 2005 | 7.9 | as Udayabhanu | as Babykuttan |
| Rock N' Roll | 2007 | · | as Chandramouli | as Vishal |
| Innathe Chinthavishayam | 2008 | · | as Gopakumar | as Dr. .Murali Krishanan |
| The Arab, The Camel, and P. Madhavan Nair | 2011 | 5.8 | as P. Madhavan Nair | as Ottakathalayan |
| Karma Yodha | 2012 | · | as Madhava Menon | as Police Officer |
| Peruchazhi | 2014 | 4.0 | as Jaganathan | as Minister Raghavan |
| Marakkar: Lion of the Arabian Sea | 2021 | 5.8 | as Kunjali Marakkar IV | as Dharmoth Panicker |